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The Nutrient-Sensing Hexosamine Biosynthetic Pathway as the Hub of Cancer Metabolic Rewiring

Alterations in glucose and glutamine utilizing pathways and in fatty acid metabolism are currently considered the most significant and prevalent metabolic changes observed in almost all types of tumors. Glucose, glutamine and fatty acids are the substrates for the hexosamine biosynthetic pathway (HB...

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Detalles Bibliográficos
Autores principales: Chiaradonna, Ferdinando, Ricciardiello, Francesca, Palorini, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025041/
https://www.ncbi.nlm.nih.gov/pubmed/29865240
http://dx.doi.org/10.3390/cells7060053