Synthesis, enzyme inhibitory kinetics mechanism and computational study of N-(4-methoxyphenethyl)-N-(substituted)-4-methylbenzenesulfonamides as novel therapeutic agents for Alzheimer’s disease

The present study comprises the synthesis of a new series of sulfonamides derived from 4-methoxyphenethylamine (1). The synthesis was initiated by the reaction of 1 with 4-methylbenzenesulfonyl chloride (2) in aqueous sodium carbonate solution at pH 9 to yield N-(4-methoxyphenethyl)-4-methylbenzensu...

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Detalles Bibliográficos
Autores principales: Abbasi, Muhammad Athar, Hassan, Mubashir, Aziz-ur-Rehman, Siddiqui, Sabahat Zahra, Shah, Syed Adnan Ali, Raza, Hussain, Seo, Sung Yum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025150/
https://www.ncbi.nlm.nih.gov/pubmed/29967717
http://dx.doi.org/10.7717/peerj.4962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025150/
https://www.ncbi.nlm.nih.gov/pubmed/29967717
http://dx.doi.org/10.7717/peerj.4962

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