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Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study

OBJECTIVE: This study was undertaken to detect if free fatty acids (FFA) induce hepatocyte senescence in L-02 cells and if huperzine A has an anti-aging effect in fatty liver cells. METHODS: L-02 cells were treated with a FFA mixture (oleate/palmitate, at 3:0, 2:1, 1:1, 1:2 and 0:3 ratios) at differ...

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Detalles Bibliográficos
Autores principales: Hu, Xiao-na, Wang, Jiao-feng, Huang, Yi-qin, Wang, Zheng, Dong, Fang-yuan, Ma, Hai-fen, Bao, Zhi-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025153/
https://www.ncbi.nlm.nih.gov/pubmed/29967757
http://dx.doi.org/10.7717/peerj.5145