Heteronemin, a Marine Sesterterpenoid-Type Metabolite, Induces Apoptosis in Prostate LNcap Cells via Oxidative and ER Stress Combined with the Inhibition of Topoisomerase II and Hsp90

Heteronemin, a marine sesterterpenoid-type natural product, possesses diverse bioactivities, especially antitumor effect. Accumulating evidence shows that heteronemin may act as a potent anticancer agent in clinical therapy. To fully understand the antitumor mechanism of heteronemin, we further expl...

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Detalles Bibliográficos
Autores principales: Lee, Man-Gang, Liu, Yi-Chang, Lee, Yi-Lun, El-Shazly, Mohamed, Lai, Kuei-Hung, Shih, Shou-Ping, Ke, Seng-Chung, Hong, Ming-Chang, Du, Ying-Chi, Yang, Juan-Cheng, Sung, Ping-Jyun, Wen, Zhi-Hong, Lu, Mei-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025191/
https://www.ncbi.nlm.nih.gov/pubmed/29890785
http://dx.doi.org/10.3390/md16060204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025191/
https://www.ncbi.nlm.nih.gov/pubmed/29890785
http://dx.doi.org/10.3390/md16060204

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