Recombinant TSR1 of ADAMTS5 Suppresses Melanoma Growth in Mice via an Anti-angiogenic Mechanism

Inhibiting tumor angiogenesis is a well-established approach for anticancer therapeutic development. A Disintegrin-like and Metalloproteinase with ThromboSpondin Motifs 5 (ADAMTS5) is a secreted matrix metalloproteinase in the ADAMTS family that also functions as an anti-angiogenic/anti-tumorigenic...

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Detalles Bibliográficos
Autores principales: Renganathan, Bhuvanasundar, Durairaj, Vinoth, Kirman, Dogan Can, Esubonteng, Paa Kow A., Ang, Swee Kim, Ge, Ruowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025205/
https://www.ncbi.nlm.nih.gov/pubmed/29891754
http://dx.doi.org/10.3390/cancers10060192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025205/
https://www.ncbi.nlm.nih.gov/pubmed/29891754
http://dx.doi.org/10.3390/cancers10060192

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