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Recombinant TSR1 of ADAMTS5 Suppresses Melanoma Growth in Mice via an Anti-angiogenic Mechanism

Inhibiting tumor angiogenesis is a well-established approach for anticancer therapeutic development. A Disintegrin-like and Metalloproteinase with ThromboSpondin Motifs 5 (ADAMTS5) is a secreted matrix metalloproteinase in the ADAMTS family that also functions as an anti-angiogenic/anti-tumorigenic...

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Detalles Bibliográficos
Autores principales:	Renganathan, Bhuvanasundar, Durairaj, Vinoth, Kirman, Dogan Can, Esubonteng, Paa Kow A., Ang, Swee Kim, Ge, Ruowen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025205/ https://www.ncbi.nlm.nih.gov/pubmed/29891754 http://dx.doi.org/10.3390/cancers10060192

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