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TGF-β Sustains Tumor Progression through Biochemical and Mechanical Signal Transduction

Transforming growth factor β (TGF-β) signaling transduces immunosuppressive biochemical and mechanical signals in the tumor microenvironment. In addition to canonical SMAD transcription factor signaling, TGF-β can promote tumor growth and survival by inhibiting proinflammatory signaling and extracel...

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Detalles Bibliográficos
Autores principales: Furler, Robert L., Nixon, Douglas F., Brantner, Christine A., Popratiloff, Anastas, Uittenbogaart, Christel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025279/
https://www.ncbi.nlm.nih.gov/pubmed/29903994
http://dx.doi.org/10.3390/cancers10060199