Cargando…

TGF-β Sustains Tumor Progression through Biochemical and Mechanical Signal Transduction

Transforming growth factor β (TGF-β) signaling transduces immunosuppressive biochemical and mechanical signals in the tumor microenvironment. In addition to canonical SMAD transcription factor signaling, TGF-β can promote tumor growth and survival by inhibiting proinflammatory signaling and extracel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Furler, Robert L., Nixon, Douglas F., Brantner, Christine A., Popratiloff, Anastas, Uittenbogaart, Christel H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025279/ https://www.ncbi.nlm.nih.gov/pubmed/29903994 http://dx.doi.org/10.3390/cancers10060199

Ejemplares similares

GLI2 Regulates TGF-β1 in Human CD4(+) T Cells: Implications in Cancer and HIV Pathogenesis
por: Furler, Robert L., et al.
Publicado: (2012)

Regulation of TGF-β Signal Transduction
por: Zhao, Bing, et al.
Publicado: (2014)

Targeting TGFβ signal transduction for cancer therapy
por: Liu, Sijia, et al.
Publicado: (2021)

Targeting TGF-β signal transduction for fibrosis and cancer therapy
por: Peng, Dandan, et al.
Publicado: (2022)

Key role for ubiquitin protein modification in TGFβ signal transduction
por: De Boeck, Miriam, et al.
Publicado: (2012)

Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks
por: Zhang, Jingyu, et al.
Publicado: (2016)

Salvianolic acid B prevents epithelial-to-mesenchymal transition through the TGF-β1 signal transduction pathway in vivo and in vitro
por: Wang, Qing-Lan, et al.
Publicado: (2010)

Maxwell's demon in biochemical signal transduction with feedback loop
por: Ito, Sosuke, et al.
Publicado: (2015)

OTUD4 enhances TGFβ signalling through regulation of the TGFβ receptor complex
por: Jaynes, Patrick William, et al.
Publicado: (2020)

TGF-beta signal transduction: biology, function and therapy for diseases
por: Tie, Yan, et al.
Publicado: (2022)

TGF-β Signaling in Progression of Oral Cancer
por: Guo, Yuanyuan, et al.
Publicado: (2023)

Effect of TGF-β(1) Stimulation on the Smad Signal Transduction Pathway of Human Peritoneal Mesothelial Cells
por: Zhang, Hao, et al.
Publicado: (2005)

let-7a suppresses liver fibrosis via TGFβ/SMAD signaling transduction pathway
por: Zhang, Yinghui, et al.
Publicado: (2019)

Chronic Exposure to TDI Induces Cell Migration and Invasion via TGF-β1 Signal Transduction
por: Han, Dong-Hee, et al.
Publicado: (2023)

TGF-β Signaling Promotes Glioma Progression Through Stabilizing Sox9
por: Chao, Min, et al.
Publicado: (2021)

Mutation of TGF-β receptor II facilitates human bladder cancer progression through altered TGF-β1 signaling pathway
por: Bian, Jing, et al.
Publicado: (2020)

Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs
por: Garofano, Kaitlin, et al.
Publicado: (2023)

TGF-β Signaling in Bone Remodeling and Osteosarcoma Progression
por: Lamora, Audrey, et al.
Publicado: (2016)

HCK promotes glioblastoma progression by TGFβ signaling
por: Wang, Zhenlin, et al.
Publicado: (2020)

Mass Spectrometry Imaging of Lipids in Human Skin Disease Model Hidradenitis Suppurativa by Laser Desorption Ionization from Silicon Nanopost Arrays
por: Fincher, Jarod A., et al.
Publicado: (2019)

Ebola Virus NP Binding to Host Protein Phosphatase-1 Regulates Capsid Formation
por: Ahmad, Asrar, et al.
Publicado: (2023)

DDB2 modulates TGF-β signal transduction in human ovarian cancer cells by downregulating NEDD4L
por: Zhao, Ran, et al.
Publicado: (2015)

MiR-10a improves hepatic fibrosis by regulating the TGFβl/Smads signal transduction pathway
por: Zhou, Guangyao, et al.
Publicado: (2016)

A unique cell population expressing the Epithelial-Mesenchymal Transition-transcription factor Snail moderates microglial and astrocyte injury responses
por: Clarkson-Paredes, Cheryl, et al.
Publicado: (2023)

EHF promotes colorectal carcinoma progression by activating TGF‐β1 transcription and canonical TGF‐β signaling
por: Wang, Lan, et al.
Publicado: (2020)

TGFβ signaling networks in ovarian cancer progression and plasticity
por: Kumari, Asha, et al.
Publicado: (2021)

Role of TGF-β receptor III localization in polarity and breast cancer progression
por: Meyer, Alison E., et al.
Publicado: (2014)

Signal Transduction in Leaf Senescence: Progress and Perspective
por: Ahmad, Salman, et al.
Publicado: (2019)

TGF-β Signaling
por: Tzavlaki, Kalliopi, et al.
Publicado: (2020)

Plasma Gelsolin Induced Glomerular Fibrosis via the TGF-β1/Smads Signal Transduction Pathway in IgA Nephropathy
por: Zhang, Lei, et al.
Publicado: (2017)

Metformin suppresses the growth of colorectal cancer by targeting INHBA to inhibit TGF-β/PI3K/AKT signaling transduction
por: Xiao, Qing, et al.
Publicado: (2022)

M2-Macrophage-Derived Exosomes Promote Meningioma Progression through TGF-β Signaling Pathway
por: Fu, Xiao-Hong, et al.
Publicado: (2022)

β-catenin-mediated Wnt signal transduction proceeds through an endocytosis-independent mechanism
por: Rim, Ellen Youngsoo, et al.
Publicado: (2020)

Free energy transduction and biochemical cycle kinetics
por: Hill, Terrell L
Publicado: (1989)

Interleukin 37 promotes angiogenesis through TGF-β signaling
por: Zhao, Mengmeng, et al.
Publicado: (2017)

Lumican promotes joint fibrosis through TGF‐β signaling
por: Xiao, Dahai, et al.
Publicado: (2020)

Crosstalk between 17β-Estradiol and TGF-β Signaling Modulates Glioblastoma Progression
por: Hernández-Vega, Ana M., et al.
Publicado: (2021)

TGF-β Signaling in Gastrointestinal Cancers: Progress in Basic and Clinical Research
por: Yokobori, Takehiko, et al.
Publicado: (2017)

Deregulation of Negative Controls on TGF-β1 Signaling in Tumor Progression
por: Tang, Jiaqi, et al.
Publicado: (2018)

Shenkang Injection for Treating Renal Fibrosis-Metabonomics and Regulation of E3 Ubiquitin Ligase Smurfs on TGF-β/Smads Signal Transduction
por: Zou, Junju, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j3ean7125r6987tuuvghn5jui6