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Novel Modulators of Proteostasis: RNAi Screen of Chromosome I in a Heat Stress Paradigm in C. elegans

Proteostasis is of vital importance for cellular function and it is challenged upon exposure to acute or chronic insults during neurodegeneration and aging. The proteostasis network is relevant for the maintenance of proteome integrity and mainly comprises molecular chaperones and two degradation pa...

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Detalles Bibliográficos
Autores principales: Kern, Andreas, Spang, Natalie, Huesmann, Heike, Behl, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025327/
https://www.ncbi.nlm.nih.gov/pubmed/29861461
http://dx.doi.org/10.3390/cells7060049