Effect of Methionine Oxidation and Substitution of α-Conotoxin TxID on α3β4 Nicotinic Acetylcholine Receptor

α-Conotoxin TxID was discovered from Conus textile by gene cloning, which has 4/6 inter-cysteine loop spacing and selectively inhibits α3β4 nicotinic acetylcholine receptor (nAChR) subtype. However, TxID is susceptible to modification due to it containing a methionine (Met) residue that easily forms...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Jie, Li, Rui, Ning, Jiong, Zhu, Xiaopeng, Zhangsun, Dongting, Wu, Yong, Luo, Sulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025358/
https://www.ncbi.nlm.nih.gov/pubmed/29925760
http://dx.doi.org/10.3390/md16060215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025358/
https://www.ncbi.nlm.nih.gov/pubmed/29925760
http://dx.doi.org/10.3390/md16060215

Ejemplares similares