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Effect of Methionine Oxidation and Substitution of α-Conotoxin TxID on α3β4 Nicotinic Acetylcholine Receptor

α-Conotoxin TxID was discovered from Conus textile by gene cloning, which has 4/6 inter-cysteine loop spacing and selectively inhibits α3β4 nicotinic acetylcholine receptor (nAChR) subtype. However, TxID is susceptible to modification due to it containing a methionine (Met) residue that easily forms...

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Detalles Bibliográficos
Autores principales:	Ren, Jie, Li, Rui, Ning, Jiong, Zhu, Xiaopeng, Zhangsun, Dongting, Wu, Yong, Luo, Sulan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025358/ https://www.ncbi.nlm.nih.gov/pubmed/29925760 http://dx.doi.org/10.3390/md16060215

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