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Oncolytic Reovirus and Immune Checkpoint Inhibition as a Novel Immunotherapeutic Strategy for Breast Cancer

As the current efficacy of oncolytic viruses (OVs) as monotherapy is limited, exploration of OVs as part of a broader immunotherapeutic treatment strategy for cancer is necessary. Here, we investigated the ability for immune checkpoint blockade to enhance the efficacy of oncolytic reovirus (RV) for...

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Detalles Bibliográficos
Autores principales: Mostafa, Ahmed A., Meyers, Daniel E., Thirukkumaran, Chandini M., Liu, Peter J., Gratton, Kathy, Spurrell, Jason, Shi, Qiao, Thakur, Satbir, Morris, Don G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025420/
https://www.ncbi.nlm.nih.gov/pubmed/29914097
http://dx.doi.org/10.3390/cancers10060205