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Acetylation Regulates Thioredoxin Reductase Oligomerization and Activity

Aims: Thioredoxin reductase 1 (TrxR1) is a cancer target and essential selenoprotein that defends the cell against reactive oxygen species and regulates cellular signaling and redox pathways. Previous cell-based studies correlated TrxR1 acetylation with modulated cellular reduction activity, yet the...

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Detalles Bibliográficos
Autores principales: Wright, David E., Altaany, Zaid, Bi, Yumin, Alperstein, Zaccary, O'Donoghue, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025699/
https://www.ncbi.nlm.nih.gov/pubmed/29117711
http://dx.doi.org/10.1089/ars.2017.7082