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Consistent inverse correlation between DNA methylation of the first intron and gene expression across tissues and species
BACKGROUND: DNA methylation is one of the main epigenetic mechanisms for the regulation of gene expression in eukaryotes. In the standard model, methylation in gene promoters has received the most attention since it is generally associated with transcriptional silencing. Nevertheless, recent studies...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025724/ https://www.ncbi.nlm.nih.gov/pubmed/29958539 http://dx.doi.org/10.1186/s13072-018-0205-1 |