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Consistent inverse correlation between DNA methylation of the first intron and gene expression across tissues and species

BACKGROUND: DNA methylation is one of the main epigenetic mechanisms for the regulation of gene expression in eukaryotes. In the standard model, methylation in gene promoters has received the most attention since it is generally associated with transcriptional silencing. Nevertheless, recent studies...

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Detalles Bibliográficos
Autores principales: Anastasiadi, Dafni, Esteve-Codina, Anna, Piferrer, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025724/
https://www.ncbi.nlm.nih.gov/pubmed/29958539
http://dx.doi.org/10.1186/s13072-018-0205-1