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Senkyunolide A protects neural cells against corticosterone-induced apoptosis by modulating protein phosphatase 2A and α-synuclein signaling

BACKGROUND: Depression is characterized by a pathological injury to the hippocampal neurons. Senkyunolide A (SenA) is one of the major active components of Dan-zhi-xiao-yao-san, which is widely used in the treatment of depression-related disorders. MATERIALS AND METHODS: In the present study, it was...

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Detalles Bibliográficos
Autores principales: Gong, Shenglan, Zhang, Jin, Guo, Zhouke, Fu, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025771/
https://www.ncbi.nlm.nih.gov/pubmed/29983543
http://dx.doi.org/10.2147/DDDT.S161748