Modes of cell death induced by tetrahydroisoquinoline-based analogs in MDA-MB-231 breast and A549 lung cancer cell lines

BACKGROUND: A and B rings of the steroidal microtubule disruptor, 2-methoxyestradiol, and its analogs can be mimicked with a tetrahydroisoquinoline (THIQ) core. THIQs are cytotoxic agents with potential anticancer activities. The aim of this in vitro study was to investigate the modes of cell death...

Descripción completa

Detalles Bibliográficos
Autores principales: Nel, Marcel, Joubert, Anna M, Dohle, Wolfgang, Potter, Barry VL, Theron, Anne E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025772/
https://www.ncbi.nlm.nih.gov/pubmed/29983544
http://dx.doi.org/10.2147/DDDT.S152718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025772/
https://www.ncbi.nlm.nih.gov/pubmed/29983544
http://dx.doi.org/10.2147/DDDT.S152718

Ejemplares similares