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Modes of cell death induced by tetrahydroisoquinoline-based analogs in MDA-MB-231 breast and A549 lung cancer cell lines

BACKGROUND: A and B rings of the steroidal microtubule disruptor, 2-methoxyestradiol, and its analogs can be mimicked with a tetrahydroisoquinoline (THIQ) core. THIQs are cytotoxic agents with potential anticancer activities. The aim of this in vitro study was to investigate the modes of cell death...

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Detalles Bibliográficos
Autores principales:	Nel, Marcel, Joubert, Anna M, Dohle, Wolfgang, Potter, Barry VL, Theron, Anne E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025772/ https://www.ncbi.nlm.nih.gov/pubmed/29983544 http://dx.doi.org/10.2147/DDDT.S152718

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