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Conformational Plasticity in the Selectivity Filter of the TRPV2 Ion Channel

Transient receptor potential vanilloid (TRPV) channels are activated by ligands and heat, and are involved in various physiological processes. In contrast to the architecturally-related voltage-gated cation channels, TRPV1 and TRPV2 subtypes possess another activation gate at the selectivity filter...

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Detalles Bibliográficos
Autores principales: Zubcevic, Lejla, Le, Son, Yang, Huanghe, Lee, Seok-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025827/
https://www.ncbi.nlm.nih.gov/pubmed/29728656
http://dx.doi.org/10.1038/s41594-018-0059-z