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Development and testing of AAV-delivered single-chain variable fragments for the treatment of methamphetamine abuse

Methamphetamine (METH) substance abuse disorders have major impact on society, yet no medications have proven successful at preventing METH relapse or cravings. Anti-METH monoclonal antibodies can reduce METH brain concentrations; however, this therapy has limitations, including the need for repeate...

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Detalles Bibliográficos
Autores principales: Hay, Charles E., Gonzalez, Guillermo A., Ewing, Laura E., Reichard, E. Elizabeth, Hambuchen, Michael D., Nanaware-Kharade, Nisha, Alam, Sinthia, Bolden, Chris T., Owens, S. Michael, Margaritis, Paris, Peterson, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025879/
https://www.ncbi.nlm.nih.gov/pubmed/29958300
http://dx.doi.org/10.1371/journal.pone.0200060