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mPEG-PLA and PLA-PEG-PLA nanoparticles as new carriers for delivery of recombinant human Growth Hormone (rhGH)

mPEG-PLA and PLA-PEG-PLA copolymeric nanoparticles with three different PLA to PEG ratios are synthesized and used for encapsulation of recombinant human Growth hormone (rhGH). The structure and composition of the synthesized copolymers were analyzed by (1)H NMR and GPC techniques. Moreover, morphol...

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Detalles Bibliográficos
Autores principales: Ghasemi, Rohollah, Abdollahi, Mahdi, Emamgholi Zadeh, Elaheh, Khodabakhshi, Khosrow, Badeli, Ali, Bagheri, Hamed, Hosseinkhani, Saman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026132/
https://www.ncbi.nlm.nih.gov/pubmed/29959339
http://dx.doi.org/10.1038/s41598-018-28092-8