Cargando…

mPEG-PLA and PLA-PEG-PLA nanoparticles as new carriers for delivery of recombinant human Growth Hormone (rhGH)

mPEG-PLA and PLA-PEG-PLA copolymeric nanoparticles with three different PLA to PEG ratios are synthesized and used for encapsulation of recombinant human Growth hormone (rhGH). The structure and composition of the synthesized copolymers were analyzed by (1)H NMR and GPC techniques. Moreover, morphol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ghasemi, Rohollah, Abdollahi, Mahdi, Emamgholi Zadeh, Elaheh, Khodabakhshi, Khosrow, Badeli, Ali, Bagheri, Hamed, Hosseinkhani, Saman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026132/ https://www.ncbi.nlm.nih.gov/pubmed/29959339 http://dx.doi.org/10.1038/s41598-018-28092-8

Ejemplares similares

Author Correction: mPEG-PLA and PLA-PEG-PLA nanoparticles as new carriers for delivery of recombinant human Growth Hormone (rhGH)
por: Ghasemi, Rohollah, et al.
Publicado: (2019)

Design, Synthesis, and Comparison of PLA-PEG-PLA and PEG-PLA-PEG Copolymers for Curcumin Delivery to Cancer Cells
por: Rostami, Neda, et al.
Publicado: (2023)

Synthesis, characterization, and evaluation of mPEG–SN38 and mPEG–PLA–SN38 micelles for cancer therapy
por: Xie, Jing, et al.
Publicado: (2016)

mPEG-PLA/TPGS mixed micelles via intranasal administration improved the bioavailability of lamotrigine in the hippocampus
por: Yu, Anan, et al.
Publicado: (2017)

Stabilization of Resveratrol in Blood Circulation by Conjugation to mPEG and mPEG-PLA Polymers: Investigation of Conjugate Linker and Polymer Composition on Stability, Metabolism, Antioxidant Activity and Pharmacokinetic Profile
por: Siddalingappa, Basavaraj, et al.
Publicado: (2015)

Smart PEG-Block-PLA/PLA Nanosystems: Impact of the Characteristics of the Polymer Blend on the Redox Responsiveness
por: Van Gheluwe, Louise, et al.
Publicado: (2023)

Evaluation of Ibuprofen Prolonged Release of Biomedical PLA-PEG-PLA Hydrogel via Degradation Mechanism
por: Nguyen, Hien Thi-Thanh, et al.
Publicado: (2023)

Preparation and In Vitro Release of Total Alkaloids from Alstonia Scholaris Leaves Loaded mPEG-PLA Microspheres
por: Zheng, Xiangyu, et al.
Publicado: (2019)

Docetaxel loaded mPEG-PLA nanoparticles for sarcoma therapy: preparation, characterization, pharmacokinetics, and anti-tumor efficacy
por: Chen, Jianhua, et al.
Publicado: (2021)

Recent advances in PEG–PLA block copolymer nanoparticles
por: Xiao, Ren Zhong, et al.
Publicado: (2010)

Synthesis of protein-coated biocompatible methotrexate-loaded PLA-PEG-PLA nanoparticles for breast cancer treatment
por: Massadeh, Salam, et al.
Publicado: (2016)

Drug-interactive mPEG-b-PLA-Phe(Boc) micelles enhance the tolerance and anti-tumor efficacy of docetaxel
por: Gong, Feirong, et al.
Publicado: (2020)

Evaluation of self-assembled HCPT-loaded PEG-b-PLA nanoparticles by comparing with HCPT-loaded PLA nanoparticles
por: Yang, Xiangrui, et al.
Publicado: (2014)

Three-Step Synthesis of a Redox-Responsive Blend of PEG–block–PLA and PLA and Application to the Nanoencapsulation of Retinol
por: Van Gheluwe, Louise, et al.
Publicado: (2020)

A comparative in vitro evaluation of self-assembled PTX-PLA and PTX-MPEG-PLA nanoparticles
por: Cui, Fei, et al.
Publicado: (2013)

Development of Epirubicin-Loaded Biocompatible Polymer PLA–PEG–PLA Nanoparticles: Synthesis, Characterization, Stability, and In Vitro Anticancerous Assessment
por: Massadeh, Salam, et al.
Publicado: (2021)

On-demand PEGylation and dePEGylation of PLA-based nanocarriers via amphiphilic mPEG-TK-Ce6 for nanoenabled cancer chemotherapy
por: Zhu, Yueqiang, et al.
Publicado: (2019)

Preparation and Characterization of Cationic PLA-PEG Nanoparticles for Delivery of Plasmid DNA
por: Zou, Weiwei, et al.
Publicado: (2009)

Assessment of Insulin Stability Inside Diblock Copolymer PEG-PLA Microspheres
por: Ibrahim, Mohamed Abbas
Publicado: (2010)

Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers
por: Movaffagh, Jebraeil, et al.
Publicado: (2022)

Preparation and Characterization of PLA-PEG-PLA/PEI/DNA Nanoparticles for Improvement of Transfection Efficiency and Controlled Release of DNA in Gene Delivery Systems
por: Amani, Amin, et al.
Publicado: (2019)

Investigation of the Effects of Chain Extender on Material Properties of PLA/PCL and PLA/PEG Blends: Comparative Study between Polycaprolactone and Polyethylene Glycol
por: Matumba, Karabo Innocent, et al.
Publicado: (2023)

Improvement of in vivo efficacy of recombinant human erythropoietin by encapsulation in PEG–PLA micelle
por: Shi, Yanan, et al.
Publicado: (2012)

Prolonged Release and Functionality of Interleukin-10 Encapsulated within PLA-PEG Nanoparticles
por: Duncan, Skyla A., et al.
Publicado: (2019)

Adenosine-Functionalized Biodegradable PLA-b-PEG Nanoparticles Ameliorate Osteoarthritis in Rats
por: Liu, Xiuling, et al.
Publicado: (2019)

Synthesis of PLA-b-PEG Multiblock Copolymers for Stealth Drug Carrier Preparation.
por: Quesnel, Richard, et al.
Publicado: (2005)

Cell-Penetrating Peptide Modified PEG-PLA Micelles for Efficient PTX Delivery
por: Shuai, Qi, et al.
Publicado: (2020)

Arenobufagin-loaded PEG-PLA nanoparticles for reducing toxicity and enhancing cancer therapy
por: Jiaying, Yang, et al.
Publicado: (2023)

Local delivery of minocycline-loaded PEG-PLA nanoparticles for the enhanced treatment of periodontitis in dogs
por: Yao, Wenxin, et al.
Publicado: (2014)

Preparation, Characterization and Properties of Porous PLA/PEG/Curcumin Composite Nanofibers for Antibacterial Application
por: Wang, Feifei, et al.
Publicado: (2019)

Transferrin Receptor-Targeted PEG-PLA Polymeric Micelles for Chemotherapy Against Glioblastoma Multiforme
por: Sun, Ping, et al.
Publicado: (2020)

Targeting lung cancer cells with MUC1 aptamer-functionalized PLA-PEG nanocarriers
por: Shahrad, Shima, et al.
Publicado: (2022)

PLA-PEG Implant as a Drug Delivery System in Glaucoma Surgery: Experimental Study
por: Germanova, Viktoriya N., et al.
Publicado: (2022)

Characterization of folic acid‐functionalized PLA–PEG nanomicelle to deliver Letrozole: A nanoinformatics study
por: Rostami, Neda, et al.
Publicado: (2021)

Preparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines
por: Alyafee, Yusra A, et al.
Publicado: (2017)

pH driven precipitation of quisinostat onto PLA-PEG nanoparticles enables treatment of intracranial glioblastoma
por: Householder, Kyle T., et al.
Publicado: (2018)

Lactoferrin-Loaded PEG/PLA Block Copolymer Targeted With Anti-Transferrin Receptor Antibodies for Alzheimer Disease
por: Li, Guichen, et al.
Publicado: (2020)

Oligo(Lactic Acid)(8)-Docetaxel Prodrug-Loaded PEG-b-PLA Micelles for Prostate Cancer
por: Repp, Lauren, et al.
Publicado: (2021)

Aggregation and Gelation Behavior of Stereocomplexed Four-Arm PLA-PEG Copolymers Containing Neutral or Cationic Linkers
por: Signori, Francesca, et al.
Publicado: (2023)

Novel PEG-graft-PLA nanoparticles with the potential for encapsulation and controlled release of hydrophobic and hydrophilic medications in aqueous medium
por: Wang, Bin, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_p6npf5q8p0h81fugls1coh07br