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The extent of extra-axonal tissue damage determines the levels of CSPG upregulation and the success of experimental axon regeneration in the CNS

The failure of mature central nervous system (CNS) projection neurons to regenerate axons over long distances drastically limits the recovery of functions lost after various CNS injuries and diseases. Although a number of manipulations that stimulate some degree of axon regeneration that overcomes t...

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Detalles Bibliográficos
Autores principales: Kim, Juhwan, Sajid, Muhammad S., Trakhtenberg, Ephraim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026156/
https://www.ncbi.nlm.nih.gov/pubmed/29959434
http://dx.doi.org/10.1038/s41598-018-28209-z