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Mechanistic insights into the augmented effect of bone marrow mesenchymal stem cells and thiazolidinediones in streptozotocin-nicotinamide induced diabetic rats

This study was designed to assess whether the protective effects of bone marrow-derived mesenchymal stem cells (MSCs) against diabetes could be enhanced by pioglitazone (PIO), a PPARγ agonist. Combined MSCs and PIO treatments markedly improved fasting blood glucose, body weight, lipid profile levels...

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Detalles Bibliográficos
Autores principales: Hamza, Alaaeldin Ahmed, Fikry, Ebtehal Mohammad, Abdallah, Wedad, Amin, Amr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026169/
https://www.ncbi.nlm.nih.gov/pubmed/29959408
http://dx.doi.org/10.1038/s41598-018-28029-1