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Exposure of Methicillin-Resistant Staphylococcus aureus to Low Levels of the Antibacterial THAM-3ΦG Generates a Small Colony Drug-Resistant Phenotype

This study investigated resistance against trishexylaminomelamine trisphenylguanide (THAM-3ΦG), a novel antibacterial compound with selective microbicidal activity against Staphylococcus aureus. Resistance development was examined by culturing methicillin resistant S. aureus (MRSA) with sub-lethal d...

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Detalles Bibliográficos
Autores principales: Weaver, Alan J., Peters, Tami R., Tripet, Brian, Van Vuren, Abigail, Rakesh, Lee, Richard E., Copié, Valérie, Teintze, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026174/
https://www.ncbi.nlm.nih.gov/pubmed/29959441
http://dx.doi.org/10.1038/s41598-018-28283-3