The adiponectin promoter activator NP-1 induces high levels of circulating TNFα and weight loss in obese (fa/fa) Zucker rats

Chronic NP-1 administration reduces body weight and hepatic steatosis despite induction of tolerance in adiponectin gene transcription with respect to the acute actions of this drug. This study explored the hypothesis that NP-1 could exert these effects through mechanisms independent of adiponectin....

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Detalles Bibliográficos
Autores principales: Decara, Juan, Serrano, Antonia, Pavón, Francisco Javier, Rivera, Patricia, Arco, Rocio, Gavito, Ana, Vargas, Antonio, Navarro, Juan A., Tovar, Ruben, Lopez-Gambero, Antonio J., Martínez, Ana, Suárez, Juan, Rodríguez de Fonseca, Fernando, Baixeras, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026175/
https://www.ncbi.nlm.nih.gov/pubmed/29959379
http://dx.doi.org/10.1038/s41598-018-27871-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026175/
https://www.ncbi.nlm.nih.gov/pubmed/29959379
http://dx.doi.org/10.1038/s41598-018-27871-7

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