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Crystallization of a human galectin-3 variant with two ordered segments in the shortened N-terminal tail

Among members of the family of adhesion/growth-regulatory galectins, galectin-3 (Gal-3) bears a unique modular architecture. A N-terminal tail (NT) consisting of the N-terminal segment (NTS) and nine collagen-like repeats is linked to the canonical lectin domain. In contrast to bivalent proto- and t...

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Detalles Bibliográficos
Autores principales: Flores-Ibarra, Andrea, Vértesy, Sabine, Medrano, Francisco J., Gabius, Hans-Joachim, Romero, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026190/
https://www.ncbi.nlm.nih.gov/pubmed/29959397
http://dx.doi.org/10.1038/s41598-018-28235-x