A GLP-1:CCK fusion peptide harnesses the synergistic effects on metabolism of CCK-1 and GLP-1 receptor agonism in mice

Combination approaches for the treatment of metabolic diseases such as obesity and diabetes are becoming increasingly relevant. Co-administration of a glucagon-like peptide-1 receptor (GLP-1R) agonist with a cholecystokinin receptor-1 (CCKR1) agonist exert synergistic effects on weight loss in obese...

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Detalles Bibliográficos
Autores principales: Hornigold, David C., Roth, Emma, Howard, Victor, Will, Sarah, Oldham, Stephanie, Coghlan, Matthew P., Blouet, Clemence, Trevaskis, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026274/
https://www.ncbi.nlm.nih.gov/pubmed/29782892
http://dx.doi.org/10.1016/j.appet.2018.05.131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026274/
https://www.ncbi.nlm.nih.gov/pubmed/29782892
http://dx.doi.org/10.1016/j.appet.2018.05.131

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