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The Role of Computed Tomography for the Evaluation of Lung Disease in Alpha-1 Antitrypsin Deficiency
Alpha-1 antitrypsin deficiency (AATD) is characterized by low serum levels of or dysfunctional alpha-1 proteinase inhibitor. In the lung parenchyma, this results in a loss of protection against the activity of serine proteases, particularly neutrophil elastase. The resultant imbalance in protease an...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American College of Chest Physicians
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026284/ https://www.ncbi.nlm.nih.gov/pubmed/29175361 http://dx.doi.org/10.1016/j.chest.2017.11.017 |