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The Role of Computed Tomography for the Evaluation of Lung Disease in Alpha-1 Antitrypsin Deficiency

Alpha-1 antitrypsin deficiency (AATD) is characterized by low serum levels of or dysfunctional alpha-1 proteinase inhibitor. In the lung parenchyma, this results in a loss of protection against the activity of serine proteases, particularly neutrophil elastase. The resultant imbalance in protease an...

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Detalles Bibliográficos
Autores principales: Campos, Michael A., Diaz, Alejandro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Chest Physicians 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026284/
https://www.ncbi.nlm.nih.gov/pubmed/29175361
http://dx.doi.org/10.1016/j.chest.2017.11.017