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Surplus fat rapidly increases fat oxidation and insulin resistance in lipodystrophic mice

OBJECTIVE: Surplus dietary fat cannot be converted into other macronutrient forms or excreted, so has to be stored or oxidized. Healthy mammals store excess energy in the form of triacylgycerol (TAG) in lipid droplets within adipocytes rather than oxidizing it, and thus ultimately gain weight. The ‘...

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Detalles Bibliográficos
Autores principales: Girousse, Amandine, Virtue, Samuel, Hart, Dan, Vidal-Puig, Antonio, Murgatroyd, Peter R., Mouisel, Etienne, Sengenès, Coralie, Savage, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026316/
https://www.ncbi.nlm.nih.gov/pubmed/29789270
http://dx.doi.org/10.1016/j.molmet.2018.05.006