Pathway analysis identifies altered mitochondrial metabolism, neurotransmission, structural pathways and complement cascade in retina/RPE/ choroid in chick model of form-deprivation myopia

PURPOSE: RNA sequencing analysis has demonstrated bidirectional changes in metabolism, structural and immune pathways during early induction of defocus induced myopia. Thus, the aim of this study was to investigate whether similar gene pathways are also related to the more excessive axial growth, ul...

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Detalles Bibliográficos
Autores principales: Giummarra, Loretta, Crewther, Sheila G., Riddell, Nina, Murphy, Melanie J., Crewther, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026464/
https://www.ncbi.nlm.nih.gov/pubmed/29967729
http://dx.doi.org/10.7717/peerj.5048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026464/
https://www.ncbi.nlm.nih.gov/pubmed/29967729
http://dx.doi.org/10.7717/peerj.5048

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