Cargando…
Pathway analysis identifies altered mitochondrial metabolism, neurotransmission, structural pathways and complement cascade in retina/RPE/ choroid in chick model of form-deprivation myopia
PURPOSE: RNA sequencing analysis has demonstrated bidirectional changes in metabolism, structural and immune pathways during early induction of defocus induced myopia. Thus, the aim of this study was to investigate whether similar gene pathways are also related to the more excessive axial growth, ul...
Autores principales: | Giummarra, Loretta, Crewther, Sheila G., Riddell, Nina, Murphy, Melanie J., Crewther, David P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026464/ https://www.ncbi.nlm.nih.gov/pubmed/29967729 http://dx.doi.org/10.7717/peerj.5048 |
Ejemplares similares
-
The retina/RPE proteome in chick myopia and hyperopia models: Commonalities with inherited and age-related ocular pathologies
por: Riddell, Nina, et al.
Publicado: (2017) -
A role for aquaporin-4 during induction of form deprivation myopia in chick
por: Goodyear, Melinda J, et al.
Publicado: (2008) -
RNA-seq and GSEA identifies suppression of ligand-gated chloride efflux channels as the major gene pathway contributing to form deprivation myopia
por: Vocale, Loretta Giummarra, et al.
Publicado: (2021) -
Bidirectional Expression of Metabolic, Structural, and Immune Pathways in Early Myopia and Hyperopia
por: Riddell, Nina, et al.
Publicado: (2016) -
Novel evidence for complement system activation in chick myopia and hyperopia models: a meta-analysis of transcriptome datasets
por: Riddell, Nina, et al.
Publicado: (2017)