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Role of ADAMTS-5 in Aortic Dilatation and Extracellular Matrix Remodeling

OBJECTIVE—: Thoracic aortic aneurysm (TAA), a degenerative disease of the aortic wall, is accompanied by changes in the structure and composition of the aortic ECM (extracellular matrix). The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family of proteases has recently bee...

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Detalles Bibliográficos
Autores principales: Fava, Marika, Barallobre-Barreiro, Javier, Mayr, Ursula, Lu, Ruifang, Didangelos, Athanasios, Baig, Ferheen, Lynch, Marc, Catibog, Norman, Joshi, Abhishek, Barwari, Temo, Yin, Xiaoke, Jahangiri, Marjan, Mayr, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026471/
https://www.ncbi.nlm.nih.gov/pubmed/29622560
http://dx.doi.org/10.1161/ATVBAHA.117.310562