Systems pharmacology using mass spectrometry identifies critical response nodes in prostate cancer

In the United States alone one in five newly diagnosed cancers in men are prostate carcinomas (PCa). Androgen receptor (AR) status and the PI3K-AKT-mTOR signal transduction pathway are critical in PCa. After initial response to single drugs targeting these pathways resistance often emerges, indicati...

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Detalles Bibliográficos
Autores principales: Ebhardt, H. Alexander, Root, Alex, Liu, Yansheng, Gauthier, Nicholas Paul, Sander, Chris, Aebersold, Ruedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026592/
https://www.ncbi.nlm.nih.gov/pubmed/29977602
http://dx.doi.org/10.1038/s41540-018-0064-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026592/
https://www.ncbi.nlm.nih.gov/pubmed/29977602
http://dx.doi.org/10.1038/s41540-018-0064-1

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