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Clonally‐related primary ALK rearranged adenocarcinoma and associated metastatic lesions

ALK rearrangement is a driver gene in non‐small cell lung cancer (NSCLC). ALK‐positive tumors are sensitive to ALK‐tyrosine kinase inhibitors (TKIs). The detection of key driver genes is crucial to enable personalized treatment. Different histomorphological patterns have different driver genes. Here...

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Detalles Bibliográficos
Autores principales: Zhu, You‐cai, Deng, Yun‐te, Wang, Wen‐xian, Xu, Chun‐wei, Zhuang, Wu, Du, Kai‐qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026599/
https://www.ncbi.nlm.nih.gov/pubmed/29737033
http://dx.doi.org/10.1111/1759-7714.12648