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Zika Virus Non-structural Protein 4A Blocks the RLR-MAVS Signaling

Flaviviruses have evolved complex mechanisms to evade the mammalian host immune systems including the RIG-I (retinoic acid-inducible gene I) like receptor (RLR) signaling. Zika virus (ZIKV) is a re-emerging flavivirus that is associated with severe neonatal microcephaly and adult Guillain-Barre synd...

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Detalles Bibliográficos
Autores principales: Ma, Jinzhu, Ketkar, Harshada, Geng, Tingting, Lo, Emily, Wang, Leilei, Xi, Juemin, Sun, Qiangming, Zhu, Zhanbo, Cui, Yudong, Yang, Long, Wang, Penghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026624/
https://www.ncbi.nlm.nih.gov/pubmed/29988497
http://dx.doi.org/10.3389/fmicb.2018.01350