Active Role of the Necrotic Zone in Desensitization of Hypoxic Macrophages and Regulation of CSC-Fate: A hypothesis

Fast-proliferating cancer cells in the hypoxic region face a shortage of oxygen and nutrients, undergo necrotic cell death, and release numerous signaling components. Hypoxia-induced chemo-attractants signal for macrophages/monocytes to clear debris and return the system to steady state. Accordingly...

Descripción completa

Detalles Bibliográficos
Autores principales: Mehrabi, Maryam, Amini, Fatemeh, Mehrabi, Shima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026632/
https://www.ncbi.nlm.nih.gov/pubmed/29988496
http://dx.doi.org/10.3389/fonc.2018.00235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026632/
https://www.ncbi.nlm.nih.gov/pubmed/29988496
http://dx.doi.org/10.3389/fonc.2018.00235

Ejemplares similares