Inhibition of Sarco-Endoplasmic Reticulum Ca(2+) ATPase Extends the Lifespan in C. elegans Worms

The sarco-endoplasmic reticulum Ca(2+)-ATPase (SERCA) refills the endoplasmic reticulum (ER) with Ca(2+) up to the millimolar range and is therefore the main controller of the ER [Ca(2+)] level ([Ca(2+)](ER)), which has a key role in the modulation of cytosolic Ca(2+) signaling and ER-mitochondria C...

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Detalles Bibliográficos
Autores principales: García-Casas, Paloma, Arias-del-Val, Jessica, Alvarez-Illera, Pilar, Fonteriz, Rosalba I., Montero, Mayte, Alvarez, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026643/
https://www.ncbi.nlm.nih.gov/pubmed/29988547
http://dx.doi.org/10.3389/fphar.2018.00669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026643/
https://www.ncbi.nlm.nih.gov/pubmed/29988547
http://dx.doi.org/10.3389/fphar.2018.00669

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