Aquaporin-4 Autoantibodies From Neuromyelitis Optica Spectrum Disorder Patients Induce Complement-Independent Immunopathologies in Mice

Neuromyelitis optica spectrum disorders (NMOSD) are central nervous system inflammatory disorders causing significant morbidities and mortality. The majority of NMOSD patients have autoimmunity against aquaporin-4 (AQP4), evidenced by seropositivity for autoantibodies against aquaporin-4 (AQP4–IgG)....

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Detalles Bibliográficos
Autores principales: Yick, Leung-Wah, Ma, Oscar Ka-Fai, Ng, Roy Chun-Laam, Kwan, Jason Shing-Cheong, Chan, Koon-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026644/
https://www.ncbi.nlm.nih.gov/pubmed/29988553
http://dx.doi.org/10.3389/fimmu.2018.01438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026644/
https://www.ncbi.nlm.nih.gov/pubmed/29988553
http://dx.doi.org/10.3389/fimmu.2018.01438

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