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Understanding the Representative Gut Microbiota Dysbiosis in Metformin-Treated Type 2 Diabetes Patients Using Genome-Scale Metabolic Modeling

Dysbiosis in the gut microbiome composition may be promoted by therapeutic drugs such as metformin, the world’s most prescribed antidiabetic drug. Under metformin treatment, disturbances of the intestinal microbes lead to increased abundance of Escherichia spp., Akkermansia muciniphila, Subdoligranu...

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Detalles Bibliográficos
Autores principales: Rosario, Dorines, Benfeitas, Rui, Bidkhori, Gholamreza, Zhang, Cheng, Uhlen, Mathias, Shoaie, Saeed, Mardinoglu, Adil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026676/
https://www.ncbi.nlm.nih.gov/pubmed/29988585
http://dx.doi.org/10.3389/fphys.2018.00775