A broader active site in Pyrococcus horikoshii CoA disulfide reductase accommodates larger substrates and reveals evidence of subunit asymmetry

Within the family of pyridine nucleotide disulfide oxidoreductase (PNDOR), enzymes are a group of single‐cysteine containing FAD‐dependent reductases that utilize a tightly bound coenzyme A to assist in the NAD(P)H‐dependent reduction of di‐, per‐, and polysulfide substrates in bacteria and archaea....

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Detalles Bibliográficos
Autores principales: Sea, Kevin, Lee, Jerry, To, Daniel, Chen, Berniece, Sazinsky, Matthew H., Crane, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026696/
https://www.ncbi.nlm.nih.gov/pubmed/29988575
http://dx.doi.org/10.1002/2211-5463.12439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026696/
https://www.ncbi.nlm.nih.gov/pubmed/29988575
http://dx.doi.org/10.1002/2211-5463.12439

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