Suppressor of IKKepsilon forms direct interactions with cytoskeletal proteins, tubulin and α‐actinin, linking innate immunity to the cytoskeleton

Suppressor of IKKepsilon (SIKE) is associated with the type I interferon response of the innate immune system through TANK‐binding kinase 1 (TBK1). Originally characterized as an endogenous inhibitor of TBK1 when overexpressed in viral infection and pathological cardiac hypertrophic models, a mechan...

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Detalles Bibliográficos
Autores principales: Sonnenschein, Halie A., Lawrence, Kenneth F., Wittenberg, Karli A., Slykas, Frank A., Dohleman, Emerald L., Knoublauch, Jilan B., Fahey, Sean M., Marshall, Timothy M., Marion, James D., Bell, Jessica K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026704/
https://www.ncbi.nlm.nih.gov/pubmed/29988566
http://dx.doi.org/10.1002/2211-5463.12454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026704/
https://www.ncbi.nlm.nih.gov/pubmed/29988566
http://dx.doi.org/10.1002/2211-5463.12454

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