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Comparative Characterization of the Sindbis Virus Proteome from Mammalian and Invertebrate Hosts Identifies nsP2 as a Component of the Virion and Sorting Nexin 5 as a Significant Host Factor for Alphavirus Replication

Recent advances in mass spectrometry methods and instrumentation now allow for more accurate identification of proteins in low abundance. This technology was applied to Sindbis virus, the prototypical alphavirus, to investigate the viral proteome. To determine if host proteins are specifically packa...

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Detalles Bibliográficos
Autores principales: Schuchman, Ryan, Kilianski, Andy, Piper, Amanda, Vancini, Ricardo, Ribeiro, José M. C., Sprague, Thomas R., Nasar, Farooq, Boyd, Gabrielle, Hernandez, Raquel, Glaros, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026752/
https://www.ncbi.nlm.nih.gov/pubmed/29743363
http://dx.doi.org/10.1128/JVI.00694-18