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Delineating Physical Organic Parameters in Site-Selective C–H Functionalization of Indoles

[Image: see text] Site-selective C–H functionalization is a great challenge in homogeneous transition-metal catalysis. Herein, we present a physical organic approach to delineate the origin of regioselective amidation of N-acylindoles through Ir(III) catalysis. Bulkiness of N-directing groups of ind...

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Detalles Bibliográficos
Autores principales: Kim, Youyoung, Park, Yoonsu, Chang, Sukbok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026776/
https://www.ncbi.nlm.nih.gov/pubmed/29974073
http://dx.doi.org/10.1021/acscentsci.8b00264