Cargando…

Nonprotecting Group Synthesis of a Phospholipase C Activatable Probe with an Azo-Free Quencher

[Image: see text] The near-infrared fluorescent activatable smart probe Pyro-phosphatidylethanolamine (PtdEtn)-QSY was synthesized and observed to selectively fluoresce in the presence of phosphatidylcholine-specific phospholipase C (PC-PLC). PC-PLC is an important biological target as it is known t...

Descripción completa

Detalles Bibliográficos
Autores principales: Liebov, Benjamin K., Arroyo, Alejandro D., Rubtsova, Natalia I., Osharovich, Sofya A., Delikatny, E. James, Popov, Anatoliy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026834/
https://www.ncbi.nlm.nih.gov/pubmed/29978148
http://dx.doi.org/10.1021/acsomega.8b00635