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Nonprotecting Group Synthesis of a Phospholipase C Activatable Probe with an Azo-Free Quencher
[Image: see text] The near-infrared fluorescent activatable smart probe Pyro-phosphatidylethanolamine (PtdEtn)-QSY was synthesized and observed to selectively fluoresce in the presence of phosphatidylcholine-specific phospholipase C (PC-PLC). PC-PLC is an important biological target as it is known t...
Autores principales: | Liebov, Benjamin K., Arroyo, Alejandro D., Rubtsova, Natalia I., Osharovich, Sofya A., Delikatny, E. James, Popov, Anatoliy V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026834/ https://www.ncbi.nlm.nih.gov/pubmed/29978148 http://dx.doi.org/10.1021/acsomega.8b00635 |
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