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SALL2 represses cyclins D1 and E1 expression and restrains G1/S cell cycle transition and cancer‐related phenotypes

SALL2 is a poorly characterized transcription factor that belongs to the Spalt‐like family involved in development. Mutations on SALL2 have been associated with ocular coloboma and cancer. In cancers, SALL2 is deregulated and is proposed as a tumor suppressor in ovarian cancer. SALL2 has been implic...

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Detalles Bibliográficos
Autores principales: E. Hermosilla, Viviana, Salgado, Ginessa, Riffo, Elizabeth, Escobar, David, Hepp, Matías I., Farkas, Carlos, Galindo, Mario, Morín, Violeta, García‐Robles, María A., Castro, Ariel F., Pincheira, Roxana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026872/
https://www.ncbi.nlm.nih.gov/pubmed/29689621
http://dx.doi.org/10.1002/1878-0261.12308