The immunoglobulin‐like domain of neuregulins potentiates ErbB3/HER3 activation and cellular proliferation

The neuregulins (NRGs) represent a large family of membrane‐anchored growth factors, whose deregulation may contribute to the pathogenesis of several tumors. In fact, targeting of NRG‐activated pathways has demonstrated clinical benefit. To improve the efficacy of anti‐NRG therapies, it is essential...

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Detalles Bibliográficos
Autores principales: Centa, Ariana, Rodríguez‐Barrueco, Ruth, Montero, Juan Carlos, Pandiella, Atanasio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026874/
https://www.ncbi.nlm.nih.gov/pubmed/29683256
http://dx.doi.org/10.1002/1878-0261.12310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026874/
https://www.ncbi.nlm.nih.gov/pubmed/29683256
http://dx.doi.org/10.1002/1878-0261.12310

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