Wingless/Wnt Signaling in Intestinal Development, Homeostasis, Regeneration and Tumorigenesis: A Drosophila Perspective

In mammals, the Wnt/β-catenin signal transduction pathway regulates intestinal stem cell maintenance and proliferation, whereas Wnt pathway hyperactivation, resulting primarily from the inactivation of the tumor suppressor Adenomatous polyposis coli (APC), triggers the development of the vast majori...

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Detalles Bibliográficos
Autores principales: Tian, Ai, Benchabane, Hassina, Ahmed, Yashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026893/
https://www.ncbi.nlm.nih.gov/pubmed/29615557
http://dx.doi.org/10.3390/jdb6020008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026893/
https://www.ncbi.nlm.nih.gov/pubmed/29615557
http://dx.doi.org/10.3390/jdb6020008

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