Mitochondrial Calcium Increase Induced by RyR1 and IP3R Channel Activation After Membrane Depolarization Regulates Skeletal Muscle Metabolism

Aim: We hypothesize that both type-1 ryanodine receptor (RyR1) and IP(3)-receptor (IP(3)R) calcium channels are necessary for the mitochondrial Ca(2+) increase caused by membrane depolarization induced by potassium (or by electrical stimulation) of single skeletal muscle fibers; this calcium increas...

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Detalles Bibliográficos
Autores principales: Díaz-Vegas, Alexis R., Cordova, Alex, Valladares, Denisse, Llanos, Paola, Hidalgo, Cecilia, Gherardi, Gaia, De Stefani, Diego, Mammucari, Cristina, Rizzuto, Rosario, Contreras-Ferrat, Ariel, Jaimovich, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026899/
https://www.ncbi.nlm.nih.gov/pubmed/29988564
http://dx.doi.org/10.3389/fphys.2018.00791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026899/
https://www.ncbi.nlm.nih.gov/pubmed/29988564
http://dx.doi.org/10.3389/fphys.2018.00791

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