Cargando…

Mitochondrial Calcium Increase Induced by RyR1 and IP3R Channel Activation After Membrane Depolarization Regulates Skeletal Muscle Metabolism

Aim: We hypothesize that both type-1 ryanodine receptor (RyR1) and IP(3)-receptor (IP(3)R) calcium channels are necessary for the mitochondrial Ca(2+) increase caused by membrane depolarization induced by potassium (or by electrical stimulation) of single skeletal muscle fibers; this calcium increas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Díaz-Vegas, Alexis R., Cordova, Alex, Valladares, Denisse, Llanos, Paola, Hidalgo, Cecilia, Gherardi, Gaia, De Stefani, Diego, Mammucari, Cristina, Rizzuto, Rosario, Contreras-Ferrat, Ariel, Jaimovich, Enrique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026899/ https://www.ncbi.nlm.nih.gov/pubmed/29988564 http://dx.doi.org/10.3389/fphys.2018.00791

Ejemplares similares

Structure of RyR1 in native membranes
por: Chen, Wenbo, et al.
Publicado: (2020)

Identification of RyR2-PBmice and the effects of transposon insertional mutagenesis of the RyR2 gene on cardiac function in mice
por: Wang, Qianqian, et al.
Publicado: (2019)

Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform
por: Venturi, Elisa, et al.
Publicado: (2018)

On the Adjacency Matrix of RyR2 Cluster Structures
por: Walker, Mark A., et al.
Publicado: (2015)

Review of RyR1 pathway and associated pathomechanisms
por: Witherspoon, Jessica W., et al.
Publicado: (2016)

RyR2 and Calcium Release in Heart Failure
por: Benitah, Jean-Pierre, et al.
Publicado: (2021)

Roles of IP(3)R and RyR Ca(2+) Channels in Endoplasmic Reticulum Stress and β-Cell Death
por: Luciani, Dan S., et al.
Publicado: (2009)

Orai, RyR, and IP(3)R channels cooperatively regulate calcium signaling in brain mid-capillary pericytes
por: Phillips, Braxton, et al.
Publicado: (2023)

Functional Characterization of a Central Core Disease RyR1 Mutation (p.Y4864H) Associated with Quantitative Defect in RyR1 Protein
por: Cacheux, Marine, et al.
Publicado: (2015)

Both Basic and Acidic Amino Acid Residues of IpTx(a) Are Involved in Triggering Substate of RyR1
por: Seo, In Ra, et al.
Publicado: (2011)

The Arianna thread: the matching of S-100 family with the RyR’s muscle receptor
por: Fulle, Stefania, et al.
Publicado: (2020)

Molecular, Subcellular, and Arrhythmogenic Mechanisms in Genetic RyR2 Disease
por: Fowler, Ewan Douglas, et al.
Publicado: (2022)

How does flecainide impact RyR2 channel function?
por: Salvage, Samantha C., et al.
Publicado: (2022)

R4496C RyR2 mutation impairs atrial and ventricular contractility
por: Ferrantini, Cecilia, et al.
Publicado: (2016)

Protein Fragmentation As a Regulatory Mechanism: Insights from Two Different Ca(2+) Channels, RyR1 and IP(3)R
por: Neyroud, Daria
Publicado: (2017)

Contextual Fear Memory Formation and Destabilization Induce Hippocampal RyR2 Calcium Channel Upregulation
por: More, Jamileth, et al.
Publicado: (2018)

Aging Impairs Hippocampal- Dependent Recognition Memory and LTP and Prevents the Associated RyR Up-regulation
por: Arias-Cavieres, Alejandra, et al.
Publicado: (2017)

Coordinated Movement of Cytoplasmic and Transmembrane Domains of RyR1 upon Gating
por: Samsó, Montserrat, et al.
Publicado: (2009)

Voltage-Dependent Modulation of Cardiac Ryanodine Receptors (RyR2) by Protamine
por: Diaz-Sylvester, Paula L., et al.
Publicado: (2009)

Zinc controls RyR2 activity during excitation-contraction coupling
por: Stewart, Alan J, et al.
Publicado: (2015)

RyR2 QQ2958 Genotype and Risk of Malignant Ventricular Arrhythmias
por: Galati, Francesca, et al.
Publicado: (2016)

Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution
por: Yan, Zhen, et al.
Publicado: (2014)

Junctional trafficking and restoration of retrograde signaling by the cytoplasmic RyR1 domain
por: Polster, Alexander, et al.
Publicado: (2018)

Dysregulation of RyR Calcium Channel Causes the Onset of Mitochondrial Retrograde Signaling
por: Roy Chowdhury, Anindya, et al.
Publicado: (2020)

Synergistic FRET assays for drug discovery targeting RyR2 channels
por: Rebbeck, RobynT., et al.
Publicado: (2022)

The biophysical properties of TRIC-A and TRIC-B and their interactions with RyR2
por: Hu, Jianshu, et al.
Publicado: (2023)

Regulation of ryanodine receptor RyR2 by protein-protein interactions: prediction of a PKA binding site on the N-terminal domain of RyR2 and its relation to disease causing mutations
por: Walpoth, Belinda Nazan, et al.
Publicado: (2015)

Characterization of a multiprotein complex involved in excitation-transcription coupling of skeletal muscle
por: Arias-Calderón, Manuel, et al.
Publicado: (2016)

Mice with RyR1 mutation (Y524S) undergo hypermetabolic response to simvastatin
por: Knoblauch, Mark, et al.
Publicado: (2013)

Identification of ATP-Binding Regions in the RyR1 Ca(2+) Release Channel
por: Popova, Olga B., et al.
Publicado: (2012)

iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin
por: Nogami, Ken’ichiro, et al.
Publicado: (2020)

Increased RyR2 activity is exacerbated by calcium leak-induced mitochondrial ROS
por: Hamilton, Shanna, et al.
Publicado: (2020)

In vivo RyR1 reduction in muscle triggers a core-like myopathy
por: Pelletier, Laurent, et al.
Publicado: (2020)

Molecular Changes in the Cardiac RyR2 With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
por: Dulhunty, Angela F.
Publicado: (2022)

Direct regulation of the cardiac ryanodine receptor (RyR2) by O-GlcNAcylation
por: Okolo, Chidinma A, et al.
Publicado: (2023)

NOX2 Inhibition Impairs Early Muscle Gene Expression Induced by a Single Exercise Bout
por: Henríquez-Olguín, Carlos, et al.
Publicado: (2016)

Structural insights into the human RyR2 N-terminal region involved in cardiac arrhythmias
por: Borko, Ľubomír, et al.
Publicado: (2014)

The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
por: Bai, Xiao-Chen, et al.
Publicado: (2016)

A chemical chaperone improves muscle function in mice with a RyR1 mutation
por: Lee, Chang Seok, et al.
Publicado: (2017)

Long-term potentiation and spatial memory training stimulate the hippocampal expression of RyR2 calcium release channels
por: Valdés-Undurraga, Ismael, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1hi7n1ej61djbmufc6an6s2sae